| 000 -LEADER |
|---|
| fixed length control field |
03208nam a22004337a 4500 |
| 003 - CONTROL NUMBER IDENTIFIER |
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| control field |
OSt |
| 005 - DATE AND TIME OF LATEST TRANSACTION |
|---|
| control field |
20250930111024.0 |
| 008 - FIXED-LENGTH DATA ELEMENTS--GENERAL INFORMATION |
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| fixed length control field |
250930b |||||||| |||| 00| 0 eng d |
| 040 ## - CATALOGING SOURCE |
|---|
| Original cataloging agency |
University of Cebu-Banilad |
| Transcribing agency |
University of Cebu-Banilad |
| 100 ## - MAIN ENTRY--PERSONAL NAME |
|---|
| Personal name |
Abejo, Joshua David S., |
| Relator term |
author. |
| 245 ## - TITLE STATEMENT |
|---|
| Title |
In vitro anti-quorum sensing activity of terminalia catappa fruit extract against serratia marcescens / |
| Statement of responsibility, etc |
Joshua David S, Abenjo [and nine others]. |
| 260 ## - PUBLICATION, DISTRIBUTION, ETC. (IMPRINT) |
|---|
| Place of publication, distribution, etc |
Cebu City, Philippines : |
| Name of publisher, distributor, etc |
University of Cebu-Banilad, |
| Date of publication, distribution, etc |
c2025. |
| 300 ## - PHYSICAL DESCRIPTION |
|---|
| Extent |
63 pages : |
| Other physical details |
colored illustration ; |
| Dimensions |
12 cm. |
| 336 ## - CONTENT TYPE |
|---|
| Source |
rdacontent |
| Content type term |
text |
| 337 ## - MEDIA TYPE |
|---|
| Source |
rdamedia |
| Media type term |
unmediated |
| 338 ## - CARRIER TYPE |
|---|
| Source |
rdacarrier |
| Carrier type |
volume |
| 504 ## - BIBLIOGRAPHY, ETC. NOTE |
|---|
| Bibliography, etc |
Incudes bibliographical references. |
| 520 ## - SUMMARY, ETC. |
|---|
| Summary, etc |
"Quorum sensing (QS) is a bacterial communication process that regulates biofilm formation and virulence, with recent research focusing on inhibiting QS to control antibiotic-resistant infections. This study investigates the anti-QS activity of Terminalia catappa fruit extract against Serratia marcescens, an opportunistic pathogen linked to hospital-acquired infections. By exploring the potential of T. catappa fruit extract to inhibit QS-regulated behaviors such as pigment production, this research aims to contribute to the development of alternative antibacterial strategies and reduce reliance on conventional antibiotics. T. catappa fruit extract was obtained using Soxhlet extraction with 95% ethanol, followed by rotary evaporation. MIC and MBC were determined via microdilution. Anti-quorum sensing activity was assessed via 96-well microplate assay. Statistical analysis was performed using one-way ANOVA and Tukey-Kramer post hoc analysis. The extract showed weak antimicrobial and quorum-sensing inhibition against S. marcescens. The MIC was 250 mg/mL with no significant bactericidal effect. At this concentration, the extract inhibited 46.69% of prodigiosin production, indicating moderate QS inhibition. The 4.5% extraction yield suggests limited potency. While previous studies highlight the antibacterial effects of leaf extracts, the fruit extract demonstrated limited efficacy. Future studies should explore the mechanisms underlying T. catappa extract's antimicrobial and quorum-sensing activities." --Abstract |
| 521 ## - TARGET AUDIENCE NOTE |
|---|
| Target audience note |
Adult |
| 541 ## - IMMEDIATE SOURCE OF ACQUISITION NOTE |
|---|
| Deans/Chairperson |
Apuhin, Mercy Milagros |
| Department |
College of Nursing |
| Subject Category |
Nursing |
| 541 ## - IMMEDIATE SOURCE OF ACQUISITION NOTE |
|---|
| Deans/Chairperson |
Apuhin, Mercy Milagros |
| Department |
College of Nursing |
| Subject Category |
Nursing |
| 546 ## - LANGUAGE NOTE |
|---|
| Language note |
Text in English |
| 650 ## - SUBJECT ADDED ENTRY--TOPICAL TERM |
|---|
| Topical term or geographic name as entry element |
Quorum-sensing activities. |
| 650 ## - SUBJECT ADDED ENTRY--TOPICAL TERM |
|---|
| Topical term or geographic name as entry element |
Fruit extract. |
| 650 ## - SUBJECT ADDED ENTRY--TOPICAL TERM |
|---|
| Topical term or geographic name as entry element |
Serratia marcescens. |
| 700 ## - ADDED ENTRY--PERSONAL NAME |
|---|
| Personal name |
Ambor, Sittie Alaicah U., |
| Relator term |
author. |
| 700 ## - ADDED ENTRY--PERSONAL NAME |
|---|
| Personal name |
Castañares, Mari Tonette J., |
| Relator term |
author. |
| 700 ## - ADDED ENTRY--PERSONAL NAME |
|---|
| Personal name |
Cubay, Exxon Z., |
| Relator term |
author. |
| 700 ## - ADDED ENTRY--PERSONAL NAME |
|---|
| Personal name |
Emborgo, Rikk Daniel, |
| Relator term |
author. |
| 700 ## - ADDED ENTRY--PERSONAL NAME |
|---|
| Personal name |
Flores, Ria Ariadne T., |
| Relator term |
author. |
| 700 ## - ADDED ENTRY--PERSONAL NAME |
|---|
| Personal name |
Jayubo, Rochelle B., |
| Relator term |
author. |
| 700 ## - ADDED ENTRY--PERSONAL NAME |
|---|
| Personal name |
Lim, Doni Corinne E., |
| Relator term |
author. |
| 700 ## - ADDED ENTRY--PERSONAL NAME |
|---|
| Personal name |
Priagula, Merch Issa R., |
| Relator term |
author. |
| 700 ## - ADDED ENTRY--PERSONAL NAME |
|---|
| Personal name |
Salgados, Peter Gabriel B., |
| Relator term |
author. |
| 942 ## - ADDED ENTRY ELEMENTS (KOHA) |
|---|
| Source of classification or shelving scheme |
|
| Type of record |
Thesis |
| 998 ## - LOCAL CONTROL INFORMATION (RLIN) |
|---|
| Encoded by |
Janna [new] |
| Date encoded |
09/30/2025 |
| 998 ## - LOCAL CONTROL INFORMATION (RLIN) |
|---|
| Encoded by |
Janna [added] |
| Date encoded |
09/30/2025 |
