Antifungal and phytochemical properties of Mindanao cinnamon (cinnamomum mindanaense) ethanolic bark extract against candida albicans / Maria Chero C. Andrino, Renette Olive L. Chua, Lasagna Kate D. Conopio, Nathalia E. Crisanto, Kezia Justine C. Dela Cruz, Ren Caryl R. Deleña, Alvie June A. Diongson, Andrei Moses B. Dreyfus, Ciarra Ysabelle E. Egnora, Agnes E. Esconde, Joshua C. Fernandez, Jan Paulo S. Gargaran, Khate B. Molinas.
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TextPublisher: Subangdaku, Mandaue City : University of Cebu - College of Medicine Foundation Inc., 2026Description: 76 pages : color illustrationsContent type: text Media type: unmediated Carrier type: volumeSubject(s): Antifungal | Antimicrobials | infectious diseases | Traditional medicine | Cinnamomum mindanaense | Candida albicans | Plant-based antifungal agentsDDC classification: Summary: "The rising prevalence of antifungal resistance and the growing number of immunocompromised patients have underscored the need for alternative antifungal agents. This study evaluated the phytochemical composition and antifungal activity of the ethanolic bark extract of Cinnamomum mindanaense (EEC) against Candida albicans. Qualitative phytochemical screening detected alkaloids, flavonoids, tannins, and saponins. Antifungal activity was assessed using the Kirby-Bauer disk diffusion method at extract concentrations of 25%, 50%, 75%, and 100%, with Nystatin and 10% DMSO as positive and negative controls, respectively. The 25% concentration produced no measurable inhibition. The 50% concentration produced a zone of inhibition comparable to Nystatin, while the 75% and 100% concentrations produced larger zones of inhibition than the positive control, with no statistically significant difference between them. These findings suggest a concentration-dependent antifungal effect of EEC against C, albicans in vitro, supporting further investigation through MIC, MFC, and cytotoxicity studies before any clinical inference can be made." --Abstract
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School of Medicine Library Thesis | T An28an 2026 (Browse shelf) | c.1 | Not for loan | 3UCSM000001640 | |
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School of Medicine Library Thesis | T An28an 2026 (Browse shelf) | c.2 | Not for loan | 3UCSM000001641 |
Includes bibliographical references.
"The rising prevalence of antifungal resistance and the growing number of immunocompromised patients have underscored the need for alternative antifungal agents. This study evaluated the phytochemical composition and antifungal activity of the ethanolic bark extract of Cinnamomum mindanaense (EEC) against Candida albicans. Qualitative phytochemical screening detected alkaloids, flavonoids, tannins, and saponins. Antifungal activity was assessed using the Kirby-Bauer disk diffusion method at extract concentrations of 25%, 50%, 75%, and 100%, with Nystatin and 10% DMSO as positive and negative controls, respectively. The 25% concentration produced no measurable inhibition. The 50% concentration produced a zone of inhibition comparable to Nystatin, while the 75% and 100% concentrations produced larger zones of inhibition than the positive control, with no statistically significant difference between them. These findings suggest a concentration-dependent antifungal effect of EEC against C, albicans in vitro, supporting further investigation through MIC, MFC, and cytotoxicity studies before any clinical inference can be made." --Abstract
Adult
School of Medicine Microbiology
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