000			03114nam a22004337a 4500
003			OSt
005			20250930113707.0
008			250930b |||||||| |||| 00| 0 eng d
040			_a University of Cebu-Banilad _c University of Cebu-Banilad
100			_aCadayday, Rhea Cristyl, _eauthor.
245			_aThe anticoagulant activity of artemisia dracunculus (wild tarragon) leaf extract as an alternative to ethylenediaminetetraacetic acid / _cRhea Cristyl Cadayday [nine others].
260			_aCebu City, Philippines : _bUniversity of Cebu-Banilad, _cc2024.
300			_aiii, 55 pages : _bcolored illustrations ; _c12 cm.
336			_2rdacontent _atext
337			_2rdamedia _aunmediated
338			_2rdacarrier _avolume
504			_aIncludes bibliographical references.
520			_a"This study investigated the anticoagulant activity of Artemisia dracunculus to (wild tarragon) leaf extract as a potential natural alternative ethylenediaminetetraacetic acid (EDTA), a widely used but environmentally persistent synthetic anticoagulant. Using methanol extraction via Soxhlet apparatus, the researchers evaluated clotting time and red blood cell morphology of human blood samples treated with the extract, comparing results with EDTA (positive control) and distilled water (negative control). Clotting time was measured using the Lee-White method, and cellular morphology was assessed microscopically through stained and unstained smears. Results showed that the extract had variable anticoagulant activity among samples, with clotting times longer than the negative control but significantly shorter than EDTA. Morphological analysis revealed that the extract preserved red blood cell integrity to some extent but was less effective than EDTA. Statistical analysis using the Kruskal-Wallis test indicated no significant difference in anticoagulant activity between the extract and EDTA (p = 0.4497). Despite demonstrating some anticoagulant potential, A. dracunculus leaf extract was concluded to be an inadequate substitute for EDTA in routine hematological applications. The study recommends further investigation with standardized extraction protocols and alternative plant parts to enhance efficacy." --Abstract
521			_aAdult
541			_xApuhin, Mercy Milagros _yCollege of Nursing _zNursing
541			_xApuhin, Mercy Milagros _yCollege of Nursing _zNursing
546			_aText in English
650			_aLeaf extract.
650			_aWild tarragon.
650			_aExtraction protocols.
700			_aCagas, Ma. Joselle, _eauthor.
700			_aDalaguido, Mary Chris, _eauthor.
700			_aFernandez, Nikko, _eauthor.
700			_aGascon, Jona Karla, _eauthor.
700			_aLerasan, Lorfil Abeto, _eauthor.
700			_aPeduche, Guerica Mariz, _eauthor.
700			_aSaladaga, Kathleen Tricci, _eauthor.
700			_aTubil, Kimberle Kaye, _eauthor.
700			_aVillacarlos, Jan Ira, _eauthor.
942			_2ddc _cTHE
998			_cJanna [new] _d09/30/2025
998			_cJanna [added] _d09/30/2025
999			_c14491 _d14491