000 03282nam a22005057a 4500
003 OSt
005 20260921132615.0
008 260921b |||||||| |||| 00| 0 eng d
040 _cUniversity of Cebu - School of Medicine
082 _2T An28an 2026
100 _aAndrino, Maria Chero C.,
_eauthor.
245 _aAntifungal and phytochemical properties of Mindanao cinnamon (cinnamomum mindanaense) ethanolic bark extract against candida albicans /
_cMaria Chero C. Andrino, Renette Olive L. Chua, Lasagna Kate D. Conopio, Nathalia E. Crisanto, Kezia Justine C. Dela Cruz, Ren Caryl R. Deleña, Alvie June A. Diongson, Andrei Moses B. Dreyfus, Ciarra Ysabelle E. Egnora, Agnes E. Esconde, Joshua C. Fernandez, Jan Paulo S. Gargaran, Khate B. Molinas.
260 _aSubangdaku, Mandaue City :
_bUniversity of Cebu - College of Medicine Foundation Inc.,
_c2026.
300 _a76 pages :
_bcolor illustrations ;
336 _2rdacontent
_atext
337 _2rdamedia
_aunmediated
338 _2rdacarrier
_avolume
504 _aIncludes bibliographical references.
520 _a"The rising prevalence of antifungal resistance and the growing number of immunocompromised patients have underscored the need for alternative antifungal agents. This study evaluated the phytochemical composition and antifungal activity of the ethanolic bark extract of Cinnamomum mindanaense (EEC) against Candida albicans. Qualitative phytochemical screening detected alkaloids, flavonoids, tannins, and saponins. Antifungal activity was assessed using the Kirby-Bauer disk diffusion method at extract concentrations of 25%, 50%, 75%, and 100%, with Nystatin and 10% DMSO as positive and negative controls, respectively. The 25% concentration produced no measurable inhibition. The 50% concentration produced a zone of inhibition comparable to Nystatin, while the 75% and 100% concentrations produced larger zones of inhibition than the positive control, with no statistically significant difference between them. These findings suggest a concentration-dependent antifungal effect of EEC against C, albicans in vitro, supporting further investigation through MIC, MFC, and cytotoxicity studies before any clinical inference can be made." --Abstract
521 _aAdult
541 _ySchool of Medicine
_zMicrobiology
546 _aText in English.
650 _aAntifungal.
650 _aAntimicrobials.
650 _ainfectious diseases
650 _aTraditional medicine.
650 _aCinnamomum mindanaense.
650 _aCandida albicans.
650 _aPlant-based antifungal agents.
700 _aChua, Renette Olive L.,
_eauthor.
700 _aConopio, Lasagna Kate D.,
_eauthor.
700 _aCrisanto, Nathalia E.,
_eauthor.
700 _aDela Cruz, Kezia Justine C.,
_eauthor.
700 _aDeleña, Ren Caryl R.,
_eauthor.
700 _aDiongson, Alvie June A.,
_eauthor.
700 _aDreyfus, Andrei Moses B.,
_eauthor.
700 _aEgnora, Ciarra Ysabelle E.,
_eauthor.
700 _aEsconde, Agnes E.
_eauthor.
700 _aFernandez, Joshua C.,
_eauthor.
700 _aGargaran, Jan Paulo S.,
_eauthor.
700 _aMolinas, Khate B.,
_eauthor.
942 _2ddc
_cTHE
998 _cVanessa [new]
_d09/21/2026
999 _c15683
_d15683